Growth hormone contributes to children's heart failure _ treatment

Growth hormone contributes to children's heart failure _ treatment
New Nicaragua (Pediatrics 2004 of Mike and El of the children's hospital of Boston of U.S.A.; 114: e452-e458) Point out, this kind of treatment has caused the left ventricle (LV) in adult and animal model to the colleague Improvement of quality and function. Too effective to the intersection of pediatrics and patient for study it, they study 8 because cardiac muscle LV caused to expand obstacle ill in function. It is beneficial to treat the heart failure infant that seem to cause to the expanding myocardium disease by recombinating people's growth hormone.
New Nicaragua (Pediatrics 2004 of Mike and El of the children's hospital of Boston of U.S.A.; 114: e452-e458) Point out, this kind of treatment has caused the left ventricle (LV) in adult and animal model to the colleague Improvement of quality and function. Too effective to the intersection of pediatrics and patient for study it, they study 8 because cardiac muscle LV caused to expand obstacle ill in function.
2 people because LV the intersection of function and person who go on decline withdraw this test alternately, the heart transplant of changing one's profession. Other people's every day growth hormone of recombination people of hypodermic injection 0.04 mg/kg, totally 6 months. The researcher notices, LV ejection fraction tends to improve during the treatment period. And 6 months later, compared with base-line level, shortening dividing into rate and other indexes (including shrinking the pressure of the end) of LV Improve notably. In addition, growth hormone higher than base-line value notably after main the intersection of effect device and the intersection of level and 6 month of IGF-1 of cardiac muscle.
Researcher summarize, conclusion these " might say growth hormone have first person who go on or continuation function " .
|