Treat the insensitive pneumonia streptococcus and infect _ to treat with spore antibiotic of very beginning
Reports such as U.S.A. kaplan,etc., employ heads of the intersection of spore and Qusong, very beginning spore oh oxime or the intersection of very beginning and the intersection of spore and furan treat insensitive the intersection of pneumonia and streptococcus beyond the central nervous system infect while being hard Damien 2.0 g/ml ] is all right. (pediatr infect dis j 2001,20:392)
In U.S.A., the intersection of pneumonia and to to able to bear medicine rate, increase constantly even antibiotic streptococcus. Penicillin, very beginning spore oh oxime or spore's sensitiveness standard of Qusong of very beginning are influenced by pneumonia streptococcus meningitis therapeutic effect to a great extent at present. When mic of penicillin is greater than or equal to 0.1 g/ml or very beginning spore's Qusong very beginning spore oh mic of oxime and greater than or equal to 2.0 g/ml, will probably treat and fail, these values have already been confirmed as able to bear the medicine indexing. But these indexes are not probably suitable for treating the pneumonia streptococcus beyond the central nervous system to infect.
Kaplan,etc., to by spore's insensitivity of Qusong of very beginning (mic was greater than or equal to from September of 1993 to August of 1999 1.0 g/ml) Pneumonia due to streptococcus last retrospect invasion and attack infection the case histories of infant beyond central nervous system, until main application amide the intersection of antibiotic and therapeutic infant analyze curative effect in the among them.
The result reveals, in the infant that the pneumonia streptococcus infects outside 2100 nerve centres, separation one of 166 is insensitive to spore's Qusong of very beginning, amide antibiotic in 100 infant's main application among them. Is from spore's Qusong mic of very beginning that 71 cases of bacteremia, 14 cases of pneumonia, 3 suppurative arthritis, a honeycomb weave inflammation in this group of infants =The streptococcus bacterial strain of pneumonia of 1.0 g/ml was caused. 6 the intersection of bacteremia and infant and 5 pneumonia infant to greater than or equal to the pneumonia streptococcus of 2.0 g/ml, cause by the intersection of very beginning and the intersection of spore and the intersection of Qusong and mic. Most infants have accepted spore's Qusong, very beginning spore oh oxime or hard treatment of furan of very beginning spore outside the intestines and stomach of a pharmaceutical or more pharmaceuticals, oral antibiotic subsequently. Besides an infant, other infants treat success. Treat a loser as a bacteremia infant uniting the immune defect seriously.
The researcher thinks, it is enough to employ spore's Qusong, hair spore oh oxime or furan of hair spore to infect outside treating the central nervous system that mic pneumonia streptococcus up to 2.0 g/ml causes pepperily, though this density is regarded as and able to bear the critical value of medicine to the antibiotic national standards committees of clinical labs of U.S.A. at present.
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