Wednesday, January 9, 2013

Which main clinical manifestation does first type hepatitis have How to confirm that diagnoses _'s general knowledge

Which main clinical manifestation does first type hepatitis have How to confirm that diagnoses _'s general knowledge
The liver function of clinical observation is examined and it is proved that relevant serum are studied, after have been infected with the first type hepatitis virus, might not present typical clinical symptom, namely might not be all found. There are quite a few of people, does not have any symptom after infecting, even it is normal to check liver function, but can produce and resist the first type hepatitis virus antibody to convalescence. Another part of people pass the incubation period of 2- 6 week, just clinical symptom appears, but there can be difference in the clinical manifestation of different persons. If some people can have generate heat, arthralgia, weak, lose the appetite, sick even vomit, abdominal distension, suffer from diarrhoea,etc., several days (generally one week) And then present jaundice, is shown as the color of urine turns to be yellow with the skin sclera yellow and dyes, this kind is first type hepatitis of acute model; Others have very much light symptom, avoid jaundice, but find while checking the liver work transaminase rises, it is inferior and clinical type to be called; Some people have no symptom, transaminase is only transient to return to normal promptly after rising, or does not rise at all, and only resist the first type hepatitis virus immunoglobulin (Ig) M (IgM) The antibody 1: More than 4000 is positive, get the convalescent IgM antibody disappear, instead of resisting the first type hepatitis virus immunoglobulin (Ig) G (IgG) The antibody is positive.
The diagnosis basis of the first type hepatitis:
First type hepatitis virus particle of detection in the patient excrement and urine.
Having illness coming on in early days, patient serum resists the first type hepatitis IgM antibody positively.
The indication masculine gender of epidemiology, can also consider as first type hepatitis; Unless it have hepatitis break out to prevail, it last hepatitis A laws prevailing,and except hepatitis B.
It is complicated and various because of the clinical manifestation of first type hepatitis, some even have no symptom, so give, diagnose, bring, sure difficult, not only want, consult, contact history, location first type hepatitis history, the patient's symptom and physical sign prevail, it and not make by liver function if you can't check as serology, determine,the latter, especially make a definite diagnosis of by bases of hepatitis first type. Employ and put and avoid France's measuring, dilute degree it as 1: 4000 IgM is still the positive one, infect the early basis; If employ resisting hepatitis A and virus IgM antibody as making a definite diagnosis of the means at the same time, can distinguish that infect convalescent acquired character immunity recently. Generally speaking, IgM belongs to one recently when greater than IgG, if IgG is greater than IgM is convalescence. The application of such specific serological index, make the diagnosis of the first type hepatitis faster, more accurate. Not only the acute model case can be made a definite diagnosis of according to resisting the first type hepatitis virus IgM antibody positively, and inferior and clinical type scarce clinical symptom, the normal case of transaminase, also can fix and diagnose on the basis that the antibody is positive.

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