Diagnostic method _'s treatment of hepatitis A

Diagnostic method _'s treatment of hepatitis A
The morbidity in the past 20 years of hepatitis A has already been reduced notably, hepatitis A was still the most common acute hepatitis. An example that the overwhelming majority of hepatitis A infects has no symptom, such as presenting symptom, the process of most cases since restrict.
Clinical manifestation: 15-50 days of incubation period. The forerunner interim excrement and urine arranges the poison and comes from the transient virus blood disease. ALT presented the peak before jaundice happened, with severe apocleisis, disgusting and vomiting. Jaundice one is generally only more than 10 days. First type hepatitis virus (HAV) There can be many kinds of atypical clinical types to infect, two points particularly attract attention: It is very common that there is no jaundice case, the inferior clinical and clinical proportion that infects can be reached (10-20) : (1)The crowd lgG of our country can reach 70%-80% resisting HAV detection rate, but the masses of the infeted do not have jaundice history, can't recollect and once have hepatitis that broke out. (2)On the other hand, some patients, especially the elderly, can have in prominent liver delaying the bile is silted up. There is no characteristic biochemistry to change, while measuring the series, very fast that ALT rises and resumes in A type than hepatitis B.
First type hepatitis is restricting disease by oneself, most patients resume within 2 months. Following up a case by regular visits to large 1 212 first type hepatitis patients while prevailing in the eighties in Shanghai, clinic and persons who returned to normal of liver function were 63.4% in 2 months, take patient of 20.40% the months for 3 piece,take 4 months for 8.6% times, take 5 months for 4.8% times, take 6 months for 1.5% times, only 1.3% when exceeding 6 one that resuming on the month. Have not found going on chronic hepatopathy, but can recur (recuring first type hepatitis) ,Even numerous outbreak, excrement and urine arrange malicious again at the same time, happen within 6 months generally.
The etiology is diagnosed: The diagnosis basis that HAV infects is with the antibody of EIA detection HAV. The intersection of serum and IgG resist HAV, say infect and immunity in HAV in the past, drip degree, continue, rise, infect recently. HAV infect after the 2-3 week, IgM resist HAV appear before clinical symptom often, keep 30-420 day, great majority within 120 days overcast to turn. Sensitive single peculiar test this - serum can win believable diagnosis.
|