Hepatitis A and clinical manifestation _ symptom

Hepatitis A and clinical manifestation _ symptom
Which typical symptoms does first type hepatitis have
The liver function of clinical observation is examined and it is proved that relevant serum are studied, after have been infected with the first type hepatitis virus, might not present typical clinical symptom, namely might not be all found.
There are quite a few of people, does not have any symptom after infecting, even it is normal to check liver function, but can produce and resist the first type hepatitis virus antibody to convalescence.
Another part of people pass the incubation period of 2- 6 week, just clinical symptom appears, but there can be difference in the clinical manifestation of different persons. If some people can have generate heat, arthralgia, weak, lose the appetite, sick even vomit, abdominal distension, suffer from diarrhoea,etc., several days ( Generally one week) And then present jaundice, is shown as the color of urine turns to be yellow with the skin sclera yellow and dyes, this kind is first type hepatitis of acute model; Others have very much light symptom, avoid jaundice, but find while checking the liver work transaminase rises, it is inferior and clinical type to be called; Some people have no symptom, transaminase is only transient to return to normal promptly after rising, or does not rise at all, and only resist the first type hepatitis virus immunoglobulin (Ig) M (IgM) The antibody 1: More than 4000 is positive, get the convalescent IgM antibody disappear, instead of resisting the first type hepatitis virus immunoglobulin (Ig) G (IgG) The antibody is positive.
Clinical manifestation of the acute first type hepatitis
Hepatitis A most only 15 days, long 45 day most, 30 day more average incubation period in virus. After being been infected with hepatitis A and virus, there are quite a few of people, there is not any symptom, even it is normal to check liver function, but can produce the first type hepatitis virus antibody to convalescence. Another part of people present clinical symptom after incubation period of 2~6 weeks, but there can be difference in the clinical manifestation of different persons. Acute jaundice type and too acute to have jaundice type on the basis of the weight of clinical symptom.
( 1) , the clinical course of acute jaundice type first type hepatitis can divide jaundice earlier stage, jaundice one, three stages of convalescence, general total course of disease about 2~4 months.
Jaundice earlier stage: Being mostly acute to get up disease, patient have, fear cold to generate heat, whole body weak and muscle ache, lose the appetite and nausea vomit, suffer from abdominal pain symptoms such as suffering from diarrhoea, and abdominal distension,etc.. Also a few patients do not have obvious jaundice and previous symptom and enter the jaundice one directly. There can be tenderness of liver district and touch a tender spot, rash, urine bilirubin is positive, check ALT and rise in liver function, resist HAV-IgM symptom such as being positive. The short one is 2~3 days, 2~3 weeks for elder, average 5~7 days.
Jaundice one: Various typical symptom and physical sign successively appeared, the annual was strengthened gradually, then it is dyed that the sclera was yellow, the skin turns yellow gradually, reach the peak during 1~2 weeks, there can be short-term stool colors at this moment to change shallowly, skin pruritus, aroused in interest and too slow, etc. About 2! Return to normal 65% patient from hepatomegaly to the intersection of rib and the intersection of reason and lower 1~3cm in the 3 week, can have slight splenomegaly. The whole jaundice one lasts 2~6 weeks, last 2 days too, it is long to 95 days or elder.
Convalescence: Jaundice disappears but has symptom to lighten even disappear clinically. , average about 1 month from this 2 week such as duration to 4 month. More than 90% of the patients are in the full restoration of getting up in disease the next half years.
( 2) It does not have jaundice type first type hepatitis that acute: It is the most common type of the clinic, accounts for more than 90% of the acute hepatitis case. Its clinical symptom is relatively light, only shown as such symptoms as weak, appetite failing, abdominal distension and liver district pain, such symptoms as a few patients have generating heat, nausea, belly that rush down. Physical sign takes hepatomegaly as the core, the spleen is swollen and very rare. Quite a lot of patients only have physical sign and liver function to change, are found during general survey. Generally return to normal in 3 months.
Some people have no symptom, transaminase is only transient to return to normal promptly after rising, or does not rise at all, and only resist the first type hepatitis virus immunoglobulin (Ig) M (IgM) The antibody 1: More than 4000 is positive, get the convalescent IgM antibody disappear, instead of resisting the first type hepatitis virus immunoglobulin (Ig) G (IgG) The antibody is positive.
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