Can first type hepatitis develop into chronic hepatitis? 's prevention and health care
Generally speaking, first type the intersection of hepatitis and overwhelming majority present limit since, few to melt while being chronic. But there are chronic reports that melted of first type hepatitis successively in recent years. Such as showing to patient's prospective result of study of 451 cases of first type hepatitis in Yugoslavia, 73 (16.2%) Present and delay course, 59 among them (13.1%) The course of disease lasts 3- 6 months, 14 (3.1%) Last to 12 month, all patient liver function returns to normal after one year. Carry on the liver and live and examine to 8 patients in 4- 24 months after the clinical and biochemical index is normal, 4 remain the change after mainly having slight hepatitis around rectum and door pulse, 2 cases of histology are basically checked normally, 2 are non- specific reactive hepatitis. The result shows, even first type hepatitis presents and delays the process, but still the benign course, liver histology does not have obvious pathological change.
Another author live, go on research very much to 25 acute first type serology, clinic, biochemistry, some liver of hepatitis, 19 cases of acute first type hepatitis that was simple finally, resumed smoothly, 3 presented and delayed the course, 3 present chronic course. 3 delaying third amino acid amino transferase (abbreviated as transaminase) of hepatitis patient Rise, last 4- 4.5 month, later through to reexamine liver function to be normal many times 10- 35 month. But two liver live, examine, histology can be seen the intersection of door and the intersection of pulse and the intersection of district and at various degrees fiber take, there are strips of connective tissue that link up and form between some pieces of pulse district, it is soaked that the lymphocytes at various degrees are chronic, the majority surmounts circle right, and reach the central district of small leaf partly, can see specific cell fat changing the sex and hepatocyte necrosis in the small leaf.
3 cases of chronic first type hepatitis, it is normal in month that a case of transaminase among them rises and is as long as 15, it has intensive lymphocytes that is soaked in the pulse district of the door that liver histology can see one at this moment, and surmount the circle board slightly, can be seen the fat of intermediate hepatocyte and change the sex and very sparse and withered and deny cells in the young leaf of liver actively, the institutional framework of liver is basically normal. Another 2 transaminase enter, up to months such as 8- 1O, separately until 11 month and 10 month liver live examine after being ill, see inflammation, but some the intersection of door and the intersection of pulse and the intersection of district and visible fiber organize hyperplasia, circle board intact.
In sum, a few first type hepatitis, not merely present and delay the process on clinic, and liver histology have a obvious one to be chronic to take, change also. So hepatitis prevent and cure worker, develop chronic question that take into, should cause enough attention to first type hepatitis.
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